Introduction: Nanotecnology could solve most of problem of biomedical and cause improve in health and pharmacology field. Also this industrial cause to eliminate food pathogenic bacteria.increase of food pathogenic bacteria and resistance them to different antibiotics caused usage of nanotechnology by researchr and pharmacologiests. Material and Methods:In this reseach is studied antimicrobial effect of nanoparticles of silver,TiO2 against on food pathogenic bacteria such as Staphylococcus aureus PTCC 1431 and Listeria monocytogenes by determination MIC and MBC. Result: Silver nanoparticle was synthezied with 103 nm of size and consentraion of 1 mili molar,nano TiO2 with 21 nm of size and consentrain of 1% have antimicrobial effect against on Staphylococcus aureus PTCC 1431 Listeria monocytogenes . Conclusion: Since that antimicrobial activity of silver ,TiO2 nanoprticles against on food pathogenic bacteria (Staphylococcus aureus PTCC 1431 and Listeria monocytogenes) is proved, is suggested to packaging antimicrobial food. Keywords: Silver nanoparticle,TiO2,,Antimicrobial effect, Staphylococcus aureus PTCC 1431 Listeria monocytogenes

Keywords: TiO2, Silver nanoparticle, TiO2, Antimicrobial effect, Staphylococcus aureus PTCC 1431 Listeria monocytogenes

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