1. Esteghamati, A., et al., Diabetes in Iran: prospective analysis from first nationwide diabetes report of National Program for Prevention and Control of Diabetes (NPPCD-2016). Scientific reports, 2017. 7(1): p. 1-10.
2. Group, N.D.D., Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes, 1979. 28(12): p. 1039-1057.
3. Hanley, A.J., et al., Prediction of type 2 diabetes mellitus with alternative definitions of the metabolic syndrome. Circulation, 2005. 112(24): p. 3713-3721.
4. Morgan, C.L., C.J. Currie, and J.R. Peters, Relationship between diabetes and mortality: a population study using record linkage. Diabetes care, 2000. 23(8): p. 1103-1107.
5. Wild, S., et al., Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes care, 2004. 27(5): p. 1047-1053.
6. Hoehn, K.L., et al., Insulin resistance is a cellular antioxidant defense mechanism. Proceedings of the National Academy of Sciences, 2009. 106(42): p. 17787-17792.
7. Goldberg, R.B., Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications. The Journal of Clinical Endocrinology & Metabolism, 2009. 94(9): p. 3171-3182.
8. Souberbielle, J.-C., et al., Vitamin D status and redefining serum parathyroid hormone reference range in the elderly. The Journal of Clinical Endocrinology & Metabolism, 2001. 86(7): p. 3086-3090.
9. Heshmat, R., et al., Vitamin D deficiency in Iran: A multi-center study among different urban areas. Iran J Public Health, 2008. 37(1): p. 72-8.
10. Baz-Hecht, M. and A.B. Goldfine, The impact of vitamin D deficiency on diabetes and cardiovascular risk. Current Opinion in Endocrinology, Diabetes and Obesity, 2010. 17(2): p. 113-119.
11. Group, E.S.S., Vitamin D supplement in early childhood and risk for Type I (insulin-dependent) diabetes mellitus. Diabetologia, 1999. 42(1): p. 51-54.
12. Hyppönen, E., et al., Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study. The Lancet, 2001. 358(9292): p. 1500-1503.
13. Fronczak, C.M., et al., In utero dietary exposures and risk of islet autoimmunity in children. Diabetes care, 2003. 26(12): p. 3237-3242.
14. Mathieu, C., et al., Seasonality of birth in patients with type 1 diabetes. The Lancet, 2002. 359(9313): p. 1248.
15. Soleymani, H., et al., Activation of human insulin by vitamin E: A molecular dynamics simulation study. Journal of Molecular Graphics and Modelling, 2019. 91: p. 194-203.
16. Soleymani, H., et al., Vitamin E induces regular structure and stability of human insulin, more intense than vitamin D3. International journal of biological macromolecules, 2016. 93: p. 868-878.
17. Trott, O. and A.J. Olson, AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. Journal of computational chemistry, 2010. 31(2): p. 455-461.
18. Van Der Spoel, D., et al., GROMACS: fast, flexible, and free. Journal of computational chemistry, 2005. 26(16): p. 1701-1718.
19. DeLano, W.L., PyMOL. 2002.
20. Kumari, R., et al., g_mmpbsa A GROMACS tool for high-throughput MM-PBSA calculations. Journal of chemical information and modeling, 2014. 54(7): p. 1951-1962.
21. Chang, X., et al., Solution structures of the R6 human insulin hexamer. Biochemistry, 1997. 36(31): p. 9409-9422.
22. Mayer, J.P., F. Zhang, and R.D. DiMarchi, Insulin structure and function. Peptide Science: Original Research on Biomolecules, 2007. 88(5): p. 687-713.
23. Weiss, M.A., Design of ultra-stable insulin analogues for the developing world. J. Health Spec, 2013. 1(2): p. 59-70.
24. Dunn, M.F., Zinc–ligand interactions modulate assembly and stability of the insulin hexamer–a review. Biometals, 2005. 18(4): p. 295-303.
25. Xiong, X., et al., Novel four-disulfide insulin analog with high aggregation stability and potency. Chemical science, 2020. 11(1): p. 195-200.
26. Mukherjee, S., et al., What gives an insulin hexamer its unique shape and stability? Role of ten confined water molecules. The Journal of Physical Chemistry B, 2018. 122(5): p. 1631-1637.
27. Akbarian, M., et al., Chemical modifications of insulin: Finding a compromise between stability and pharmaceutical performance. International journal of pharmaceutics, 2018. 547(1-2): p. 450-468.
28. Tomasi, T., et al., Insulin half-life in normal and diabetic subjects. Proceedings of the Society for Experimental Biology and Medicine, 1967. 126(1): p. 315-317.