1- Faculty of medicinal plants, Amol University of Special Modern Technologies, Amol, Iran. , mahboobeh.zare93@gmail.com
2- Faculty of medicinal plants, Amol University of Special Modern Technologies, Amol, Iran
3- Department of Biotechnology, Amol University of Special Modern Technologies, Amol, Iran.
4- Faculty of medicinal plants, Amol University of Special Modern Technologies, Amol, Iran.
2- Faculty of medicinal plants, Amol University of Special Modern Technologies, Amol, Iran
3- Department of Biotechnology, Amol University of Special Modern Technologies, Amol, Iran.
4- Faculty of medicinal plants, Amol University of Special Modern Technologies, Amol, Iran.
Abstract: (37 Views)
Cancer is one of the leading causes of mortality worldwide. this multifactorial disease characterized by complex molecular landscape and altered cell pathways that results in an abnormal cell growth. One of the recent strategies to combat cancer is application of phytochemicals. phytochemicals including phenolics, alkaloids, terpenoids, carotenoids, phytosterol, saponin and organosulfur compounds which play important roles in the prevention and treatment of cancer. The pharmacological use of phytochemicals compounds is frequently limited by their low bioavailability and solubility as they are mainly lipophilic compounds. The nanotechnological approach improves bioavailability, and inhences solubility. In the present review we aim to summarize challenges of phytochemical compounds in cancer treatment and the status of phytochemical based nanoformulations in improving the therapeutic response.
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