Volume 2, Issue 1 (2011)
JMBS 2011, 2(1): 0-0 |
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Increasing Tropane Alkoloids Synthesis and h6h gene expression by charbohydrates. JMBS 2011; 2 (1)
URL: http://biot.modares.ac.ir/article-22-9903-en.html
URL: http://biot.modares.ac.ir/article-22-9903-en.html
Abstract: (11535 Views)
Atropine and scopolamine are two important tropane alkaloids, widely use as anticholinergic drugs. Such as most solanaceae plants, Atropa belladonna produces these two tropane alkaloids. Carbohydrates are not only act as carbon sources for solanaceus plants in vitro cultures, but also have some effects as signal molecules on tropane alkaloids metabolism. Effect of sorbitol, mannitol and sucrose on growth, chlorophyll, hyoscyamine and scopolamine contents, and hyoscyamine 6- beta hydroxylase (H6H) gene expression, investigated. These treatments decreased the growth of plantlets but increased chlorophyll, hyoscyamine and scopolamine contents. The treatments increase h6h gene expression in different organs of Atropa belladonna plantlets. There was an agreement between h6h expression pattern and scopolamine contents.
Received: 2010/10/14 | Accepted: 2011/03/5 | Published: 2011/09/19
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