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Showing 3 results for Aghamiri
Volume 1, Issue 1 (3-2013)
Abstract
Aims: Evaluation of Patient Satisfaction (PS) is one of the most essential factors in improving the quality of healthcare systems. The aim of this study is to determine the norms and to evaluate the validity and reliability of the Najmiyeh Outpatients Satisfaction Questionnaire (NOSQ). Methods and Materials: This study has been conducted on 240 outpatients in Najmiyeh subspecialty hospital (Tehran-Iran) in 2011. They were selected using the proportional simple random sampling method. Following the confirmation of the content validity, we considered the construct validity and reliability applying Confirmatory Factor Analysis (CFA) and Explanatory Factor Analysis (EFA) and Cronbach's Alpha. Also, SPSS and AMOS version 18 were used for data analysis. Findings: The sample population consisted of 240 subjects, including 132 females (55.1%) and 108 males (44.9%). The EFA reported three important factors in this regard, with a variance of 54% and Kaiser-Meyer-Olkin index of 0.82, all approved by the CFA (RMSEA= 0.04, CFI= 0.96). The outpatients' satisfaction factors were: “hospital information system, treatment and conditions”. The reliability of the questionnaire was reported at %71 based on the Cronbach's alpha. Conclusions: Both validity and the reliability indexes of the NOSQ have been reported at a desirable level; therefore it can be used as a valid and reliable instrument to measure the outpatients' satisfaction.
Volume 1, Issue 2 (6-2013)
Abstract
Aim: Patients' satisfaction (PS) is a dominant concept in medical care, due to the gap in the literature on Persian version of PS instruments, this study has conducted with aim to analyze the validity and reliability of self-designed Najmiyeh Inpatient Satisfaction Questionnaire (NISQ). Methods: This study was carried out on 247 inpatients that came in Najmiyeh subspecialty hospital in Tehran (the capital city of Iran) during year 2011 who were selected by proportional stratified sampling method. Statistical analysis used: In this study, after checking content validity we used confirmatory and explanatory factor analysis and Cronbach's Alpha in order to examine construct validity and reliability, respectively. SPSS (version18) and AMOS (version 20) programmer were used to analyze data. Findings: Samples consisted of 247 subjects (222 women (90%) and 25 men (10%)). The explanatory factor analysis showed 5 factors with 64% total variance and 0.91 Kaser-Meyer-Olkin Index, the result also confirmed with confirmatory factor analysis (PNFI=0.71, RMR=0.03, PCFI=0.76). Extracted factors consisted of: “satisfaction from nursing services and their behaviour”, “satisfaction from one’s doctor”, “satisfaction from inpatient department”, “companions’ satisfaction”, “satisfaction from one’s room”. Also the questionnaire’s reliability was 0.96 using the Cronbach's Alpha method. Conclusions: Because validity and reliability indexes of NISQ were reported in suitable range, we can confirm that this questionnaire is a valid and reliable tool for measuring inpatient satisfaction.
S.m.r. Aghamiri , S. Akbari-Karadeh , P. Tajer Mohammad Ghazvini , S. Ghorbanzadeh Mashkani ,
Volume 9, Issue 2 (Spring 2018)
Abstract
Aims: In recent years, magnetotactic bacteria and their magnetic nanoparticles (magnetosomes) were considered in different fields of science, including medicine, biotechnology, and nanobiotechnology due to their novel and unique magnetic properties. The present study was performed with the aim of evaluating the effect of temperature and reducing agent on labeling of magnetosomes with 188Re and biodistribution of labeled magnetic nanoparticles.
Materials and Methods: In this experimental study, Alphaproteobacterium MTB-KTN90 and sonication extraction method were used for the extraction of magnetic nanoparticles. After bacterial lysis, the magnetic nanoparticles produced by electron microscope were investigated and tin (II) chloride, as reducing agent, was used to check the labeling efficiency and rats were used to examine the biodistribution of the labeled magnetosomes.
Findings: The highest efficiency in magnetosome labeling experiments was 11100kBq in the initial activity, which decreased with increasing activity. The increase in temperature did not have much effect on increasing the labeling efficiency. The labeling value in the absence of a reducing agent was 721.5kBq, while at a concentration of 2mg of this agent, the labeling value increased to 10745.91kBq. After the injection of magnetosomes through the sublingual vein of the rat, the magnetosomes accumulated in the liver.
Conclusion: Magnetosomes extracted from Alphaproteobacterium MTB-KTN90 have a high potential for labeling by 188Re. Increasing temperature does not affect the labeling efficiency, but tin (II) chloride is a very important factor in optimizing the labeling efficiency, and the highest accumulation of magnetosomes labeled with 188Re after injection is in the liver of the rat.
