Showing 6 results for Dorostkar
Volume 3, Issue 3 (fall 2022)
Abstract
Problem Statement: Islamic city and urban planning is an interesting, challenging, and audience-oriented topic. What prioritizes Islamic research and urban planning is an Islamic government and the current Islamic laws in that government. The development of the earth must be in the service of the rational life of man, and the eternal life of man is superior to mere development.
Purposes: The purpose of this article is to give an overview of the existing approaches in Islamic urban planning studies and to introduce the integrated studies approach in Islamic urban planning.
Aims: The present study is about the subject in terms of developmental purpose, descriptive implementation in terms of implementation, and qualitative content analysis of resources in terms of research method. The required data has been collected by the documentary method.
Findings: This article tries to study the basic principles of the Islamic city by re-reading the opinions and works and the views of experts. For this purpose, he examines their opinions according to the proposed categories in a theoretical framework and sees differences in views and expressions of different concepts about the Islamic city.
Conclusion: The results show that the city and Islamic urban planning should refer to the general principles of Islam and not go into details and follow the intellect to form the city. And this principle will lead to the victory of the general principles of Islam over the city. As a forthcoming solution in Islamic urban planning studies, we can refer to the comprehensive plan of Islamic management called Najma, which as an upstream and comprehensive document can enter the field of Islamic studies in various fields and complement interdisciplinary studies.
Volume 3, Issue 4 (Fall 2021)
Abstract
Urban management governance is stated when it is intended to form in the city administration by facilitating the process, creating and increasing the participation of citizens in urban management framework. At this point, an assessment of urban management frameworks is imported and used. Challenges occur when evaluating these frameworks to enter extraordinary components. With these interpretations, the main problem in the metropolitan city of Tehran is the expediency in urban governance. The main question is that “what is the role of expediency in urban management which aims to facilitate the participation of citizens in the city? In this research, the PROMETHEE method was recognized as one of the best decision-making methods. The why of choosing this method is that it considers several criteria for comparing methods. Some of these criteria include ease of use, interpretation of the parameters, the sustainability of the results, the level of user interaction with the model and the ease of understanding the results. The framework of the urban administration framework of Tehran is composed of 14 main components and 53 sub-components, which is based on 14 main components including accountability, transparency, participation, effectiveness, equality, sustainability, observation and planning, legitimacy and bureaucracy, civil capacity, service provision, efficient economics, communication, communication, security, and expediency. The component of the expediency, giving the conditions of the status of Iran's sovereignty, has shown a completely significant effect.
Volume 8, Issue 4 (fall 2022)
Abstract
Backgrounds: SARS-COV-2 infection is not always correlated with protection. Antibody seroprevalence in unvaccinated individuals, which is usually measured by N-specific antibodies, is not necessarily correlated with protection, while antibodies against S protein show a better correlation with protection due to its neutralizing epitopes. In this study, we tried to improve our conception of the hidden perspective of SARS-COV-2 in epidemiological reports and investigate anti-S antibody prevalence among anti-N antibody-positive asymptomatic and mildly symptomatic patients.
Materials & Methods: Blood samples were collected from asymptomatic or mildly symptomatic volunteer participants and symptomatic hospitalized patients with negative PCR results from May 30 to June 17, 2020. Detection of SARS-COV-2 antibodies was done using an ELISA kit targeting N or S protein.
Findings: Totally, 716 samples from volunteer participants and 81 samples from symptomatic hospitalized patients with negative PCR results were evaluated. The test performance-adjusted seroprevalence (95% CI) of SARS-COV-2 antibody was 17.3% (8.8-25.8%) for anti-N IgG in volunteers and 25.5% (12.8-39.7%) for anti-N and anti-S IgM in hospitalized patients. Among anti-N IgG positive infected individuals, 49.2% (21.4 and 78.8%) were anti-S antibody positive.
Conclusion: The results showed that SARS-COV-2 infection sometimes occurs in individuals without symptoms or with mild symptoms, but in more than half of them, the produced antibody is not protective. The findings of hospitalized patients showed that the combination of IgM assay with real-time PCR improved the disease diagnosis by more than 25% in cases with negative molecular test results.
Sahar Karimi, Shahram Nazarian, Fattah Sotoodehnejadnematalahi, Roohollah Dorostkar, Jafar Amani,
Volume 14, Issue 1 (FALL 2023)
Abstract
Given the global epidemic of COVID-19, it is important to design a vaccine for prevention. The virus belongs to the beta-coronavirus family and forms appendages on the surface of the glycoprotein spike virus membrane. Studies on SARS-CoV-1 and related MERS-CoV vaccines have shown that the spike protein on the virus surface is a suitable target for the vaccine. In this experimental study, we compare the recombinant fragment of spike protein (rfsp) expressed in the eukaryotic host CHO-K1 cell and prokaryotic E. coli in terms of immunogenicity, neutralizing activity, and epitopes recognition Similar to the virus strain and the ability to bind to the serum of improved patients, in two types of alpha and delta variants. The results showed that both rfSP proteins are a potential new antigen candidate for the development of the Covid 19 vaccine, but the CHO cell maintains the biological activity of the protein by performing post-translational modification processes such as glycolysis. This increases the present likelihood of developing virus-like epitopes and increases the titer of rfsp-specific antibodies in the serum of immunized mice. Therefore, priority is given to rfsp expressed in CHO cells to evaluate vaccine efficacy.
Volume 14, Issue 3 (5-2012)
Abstract
The objective of this study was to determine the inbreeding depression on growth traits in Moghani sheep. Pedigree information of 8836 animals collected during the years of 1987 to 2006 by Moghani Breed Center in Jafar Abad Moghan, were used for analysis. The base population year was 1988. Analysis of the records was performed by ASReml software. Inbreeding depression was estimated as the regression of performance on the individual inbreeding coefficients via fitting an animal model. The mean inbreeding for all animals, females and males, were 0.500, 0.515 and 0.484 %, respectively. Totally, 24.22 % of all the animals were inbred. The mean of inbreeding for inbreed animals was 2.062 %. The rate of increased inbreeding per year for all animals was 0.05%. The inbreeding depression for body weight traits at birth, 3, 6, 9 and 12 months of age was , respectively, -0.007, - 0.291, - 0.026, -0.018 and -0.041 kg, per 1% increase in individual coefficient.
Volume 16, Issue 92 (october 2019)
Abstract
Apricot is a climacteric fruit with high respiration rate, which ripen quickly during the postharvest stage and has a short shelf life. Therefore, the use of environmentally friendly compounds for delaying the ripening process is one of the safe methods for extending the shelf life and reducing the postharvest losses of this fruit. Hence, the effect of some chemical treatments on quality and shelf life of apricot fruit cultivar ‘Shahroudi’ was carried out in a completely randomized design with seven treatments and four replications. The treatments were fruit immersion in individual or combination solutions of salicylic acid, oxalic acid and nitric oxide at concentrations of 2, 2 and 1 mM, respectively. The fruits were then packed and transferred to 2 °C with relative humidity of about 85 ± 5%. After 4 weeks of storage, their chemical, sensorial and qualitative properties were evaluated. The results showed that the highest fruit firmness was obtained in salicylic acid (11.46N) and nitric oxide treatment (9.85N). Soluble solids content had the highest values in salicylic acid and combined treatments, respectively. In terms of organoleptic evaluation, salicylic acid and nitric oxide treatments significantly preserved the texture, taste and appearance of the fruits. The highest shelf life was observed in salicylic acid (27.5 days) and nitric oxide (25.5 days) treated fruits, while it was only 14 days in control. In general, it can be concluded that salicylic acid and nitric oxide were the best treatments.
