Showing 12 results for Ghafoori
Volume 0, Issue 0 (Articles accepted at the time of publication 2024)
Abstract
The capacity of Qur'anic stories, which are texts full of meanings, always provides the ground for using various methods and approaches of studying and analyzing the text, so that the intertwined and overlapping layers of the text are opened and the process of making meaning becomes clearer for the audience. The present article is based on the model of the "semiotics square", one of the models of Grimas, the founder of the Paris School of Semiotics, which analyzes the mechanism of meaning construction in the text production process. The "semiotics" box teaches us the methodical reading of a text. Using this model, this article intends to analyze the textual structures of the duality of "honor and humiliation" in the Qur'anic story of Yusuf (AS) and explain the process of formation of their meanings in the Qur'anic discourse of this story. The conclusion of this research for the expansion of the semiotic square is that based on this model, it is possible to continuously move poles and categories in a text; This means that in the process of discourse, although in the dual analysis of "humiliation and dignity" we encounter eight forms at the level of content, but contrary to the usual that at the level of expression, the corresponding formulations can be several people or several things .In the story of Yusuf (AS), the corresponding formulation is one person, namely Yusuf the Prophet (AS
Volume 2, Issue 1 (3-2016)
Abstract
Background: Today a large number of bacterial amylases are available commercially in industry. The goal of the present study was purification and biochemical characterization of an extracellular thermostable alkaline α-amylase from the novel moderately halophilic, Bacillus persicus
from the Aran-Bidgol, Iran.
Methods
: Purification of enzyme, was carried out by acetone precipitation, ultrafiltration and Q-Sepharose cation exchange chromatography.
Results
: The purified native enzyme showed a molecular mass of 53 kDa composed of a monomer by SDS–PAGE. The optimum pH, temperature and NaCl concentration were 10, 45 ∘C and 0.85 M respectively. It retained 50% of activity at 1.25 M NaCl and about 73% of activity at highly alkaline pH of 10.5, therefore it was a moderately halophilic and also can activate by divalent metal ions especially Ca2+ and Mg2+. The apparent values of Km and Vmax were obtained 1.053 mg/ml and 356μ/min respectively.
Conclusion
: In the present study we report the purification and characterization of a moderately halophilic α-amylase from a newly isolated Bacillus persicus. The purified enzyme shows interesting properties useful for industrial and biotechnological applications. The molecular cloning and structural studies of this α-amylase are in progress in our laboratory.
Volume 2, Issue 2 (Summer 2014)
Abstract
The title of the story is the threshold to the mysterious world of the text. Thus it must be selected artistically to show the quality of the text, despite its quantity and restrictions. Sometimes, the title sheds light on the world of the text and lights the text`s whole material, but sometimes, it hides the text and the reader does not resieve any sign of it. It makes a tension in the mind of the reader to draw him/her to the text, and makes him/her to arrange his/her disturbed mind by reading the text and finding the meaning of it. This research is aims to investing ate the most important textual and extra textual factors, which are efficient in choosing the title of Sadeq Hedayat and Zakaria Tamer`s works, and study the structure and context of the titles and their relation with intra-textual and extra-textual factors that are used to hide the meaning of the text. have several res sons. Attracting the reader and closed political conditions (extra-textual factors) are the main reasons. These titles show the familiarity of the two writers with rhetorical devices. Also they are the reflection of the difficulties and hard conditions of the people`s life and the writer`s current cultures.
Volume 4, Issue 4 (12-2016)
Abstract
Aim: The main purpose of this study was to investigate the effect of parental support of their children’s participation in recreational sports classes.
Methods: This study was a functional-descriptive survey in which a self-administered questionnaire was used for data collection. It consisted of variables including psychological, cultural, social, emotional, economical and informational support. The face and content validities were evaluated by 10 professors specialized in sport education. Moreover, confirmatory factor analysis assessed the validity of questionnaire. The reliability of the questionnaire was assessed by Cronbach's alpha in the pilot study. The study population included all children participating in the recreational sports classes at summer 2016 out of whom a sample of 300 was selected randomly.
Findings: The results showed that all variables (Psychological, Cultural, Social, Emotional, Economical and Informational support) encouraged the participation of children in sports activities.
Conclusion: Generally, the results showed that parental support increased the children’s participation in sport activities, which, in turn, improved the physical and mental health of young generation in the society.
Hosein Ghafoori, , ,
Volume 7, Issue 1 (6-2016)
Abstract
Abstract- Silibinin a natural flavonoid has been reported to induce cell death in various types of cancers and also in endothelial cells which shows its anti-angiogenesis effect. However, its molecular mechanism is not clearly defined. In this article, we provided evidence for one of the mechanisms by which Silibinin induces apoptosis in HUVEC. For this purpose, HUVECs were grown on 96 well plates and cell viability was measured by MTT assay and IC50 was determined as 143μM after 24 hr of treatment by Silibinin. Caspase-9 activity in dose dependent (100-300μM) and time dependent (24,48 and 72hr) treatment by Silibinin was assessed using chromogenic substrate LEHD-pNA. Maximum activity of caspase 9 was in 100 μM of silibinin after 48 hours of treatment. DNA fragmentation was analyzed by gel electrophoresis. Cells were incubated with different concentrations of silibinin (100-400μM) and DNA that was extracted from cells which were incubated by 400 μM of silibinin formed a smear on agarose gel. Data obtained from this study showed the ability of Silibinin to inhibit HUVEC cell proliferation through apoptosis induction which indicates the anti-angiogenesis effect of this compound.
Volume 8, Issue 1 (winter 2023)
Abstract
Aims: One of the important risk factors for MusculoSkeletal Disorders (MSDs) is poor posture at work. The aim of this was to evaluate the posture ergonomics of Kerman potters using Rapid Entire Body Assessment (REBA) and Quick Exposure Check (QEC) methods.
Method and Materials: In this study, detailed evaluations of working postures of the participants were done through photography and filming. To determine the risk levels of the disorders, the workers' physical condition was assessed using the Rapid Entire Body Assessment (REBA) and Quick Exposure Check (QEC) methods. Ergonomic assessment of jobs was done in postures that were either more frequent or the most difficult position of the body in that job.
Findings: According to REBA method, 77.7% of the postures had a moderate risk level which need corrective measures. Moreover, 22.2% of the postures had a high risk level which corrective measures should be taken soon. According to QEC method, 22.2% of the postures were acceptable. About 11.1% of the postures need further study and 66.6% of the postures had a high risk level that need further study and corrective action in the near future.
Conclusion: The results of this study indicate that work postures of studied potters have moderate to high risk and require immediate corrective action to improve working conditions through ergonomic training.
Volume 9, Issue 17 (Spring & Summer 2022)
Abstract
Since Quran has been revealed in Arabic, a precise perception and translation of its words has always been of special importance for non-Arabic speakers. Paying attention to the precise meaning of words is seen as the most essential step in offering a precise translation and staying faithful to the text. Here, the word 'asaver', which has been used four times in the Quran and introduced as one of the gifts from heaven, is especially important. Using a descriptive-analytic method, the current research examines the meanings of the word 'asaver' and analyzes the Persian translations of this term stage by stage. At first, the meaning of the word 'asaver' was analyzed lexically, stylistically and using the opinions of the interpreters and historians. The results of the examinations at this stage showed that 'asaver' is the plural form of 'sevar' meaning any kind of ornament related to the hand and worn like a ring. At next stage, the Persian translations of the Quran were investigated. The results at this later stage reveal that all translators have been affected by the result of the first stage. What matters is that none of the lexicologists, interpreters and translators have heeded the otherworldly nature of the concept of asaver, treating it as synonymous with the word 'asverah' that has been used once in an Ayah and refers to the worldly ornamentation.
F. Vahdani, H. Ghafoori , S. Sarikhan,
Volume 10, Issue 2 (Spring 2019)
Abstract
Hsp70 family members are central components of the cellular network of molecular chaperones and folding catalysts. The gene encoding a protein related to Hsp70 or DnaK in the domain bacteria is called dnaK. DnaK proteins are involved in de novo protein folding, formation, and disassembly of protein complexes and degradation of misfolded proteins. The gene dnaJ which codes for Hsp40 in bacteria, modulate the activities of DnaK by acting as co-chaperone. In the present study, we cloned and expressed DnaK from Bacillus halodurans Guj1 were identified. The dnaK gene of B. halodurans was successfully expressed in E. coli BL21 (DE3) using pET-28a+ expression system. The open reading frame of the cloned gene contained 1839bp and encoded 612 amino acid residues. Calculated molecular weight and pI of the protein were 66.18kDa and 4.55 respectively. The deduced amino acid sequence of B. halodurans Guj1 showed about 60% identity with the E. coli counterpart. The 3D structure of dnaK from B. halodurans was constructed using the crystal structure of human HSP70 chaperone BiP as the template, which showed an identity of 88.8% together. Partially purified recombinant DnaK by heat treatment showed a band at approximately 70kDa on SDS-PAGE. Our findings showed that the recombinant DnaK improved the refolding efficiency of the carbonic anhydrase by 27% after 60min at 54°C. According to the results obtained, DnaK from B. halodurans can potentially be used for improving the functional properties of enzymes and proteins in various applications.
Volume 14, Issue 1 (March & April 2023 (Articles in English & French) 2023)
Abstract
The present study explored the effect of explicit Communication Strategies (CSs) instruction on Iranian EFL learners’ usage of these strategies in their educational tasks at different proficiency levels. To conduct the study, the researchers chose 20 Iranian EFL teachers and their 150 students at two universities in Tabriz, Iran. Accepting a mixed-methods design, the researchers used a questionnaire, an English language proficiency test, and a semi-structured interview to collect the required data. The findings indicated that after receiving communication strategy instruction, teachers and students had positive attitudes toward the usefulness of CSs in the language learning process. However, learners in different proficiency levels had different preferences toward CSs. While advanced learners showed their inclination to use compensation strategies, intermediate learners preferred to use metacognitive. Elementary learners favoured using cognitive CSs. These differences can be attributed to individual differences and contextual factors that suggest pedagogical implications for both teachers and students and provide tentative subjects for further studies.
Volume 14, Issue 2 (5-2014)
Abstract
Inspired by the muscle arrangement of the octopus and skeleton of the snakes, a wire-driven serpentine robot arm has been simulated and constructed in this article. The robot links which are connected via flexible beam act as the snake backbone. Instead of using motors at each joint, four sets of wire are employed as octopus muscles to drive the robot arm. For the spatial inverse kinematics, after determining the generalized coordinates of the system, governing algebraic equations of the system including constraint equations of the joints and cables and favorable movements have been determined. For displacement analysis, these equations have been solved using the Newton-Raphson method. Using this method robot workspace has also been determined. For the inverse dynamics of the robot, cables tension force has been considered as external forces. Using Embedding technique with specified constraint matrix, mass matrix and acceleration vectors that are determined from inverse kinematics, cables tension force and torque of motors are specified. To validate the snake robot model, a prototype has been built and programmed for some circular and arcuate routs. Travelled pass by end effector have been obtained. Comparing the results with the desired path, accuracy of the designed robot has been investigated.
Volume 16, Issue 4 (1-2013)
Abstract
With the increasing pace of science and knowledge in today, s world, the company in order to comply with the condition environment variable to use communication technology and capital investment in this technology is growing rapidly. Performance evaluation is one of the main concerns for monitoring this agreement. Recently applied the theory of data envelopment analysis (DEA) and grey theory for performance evaluating has been highly regarded. Considering the importance of telecommunications as a leader in the field of communication technology and necessary to evaluate the performance of these two techniques have been used in this study. For this mining first set of criteria in evaluating the financial performance of telecommunication and the importance (weight) each was determined using the number of grey. Then, technique of using DEA model for evaluating and ranking the telecommunications companies were presented. The result indicates that the major telecommunication companies province in Markazi, Tehran and Khuzestan have the best financial performance.
Volume 21, Issue 5 (9-2019)
Abstract
Artemisia annua L. is an important medicinal plant used as an original source of artemisinin for treating malaria. Although there is a wide distribution of A. annua in Hyrcanian Areas (Mazandaran, Guilan, and Golestan Provinces in N Iran), no considerable effort has been made for diversity assessment. In this study, morphological, phytochemical, and molecular characterization of A. annua accessions in this area were assessed using 4 quantitative characteristics (height, fresh weight, dry weight, and trichome density), artemisinin content, and 15 ISSR primers. Using these traits, a high level of morphological, phytochemical and molecular diversity was revealed among A. annua accessions in the provinces (populations) of Hyrcanian Areas. At inter-population level, the highest value of artemisinin was observed in Mazandaran Province. Moreover, significant correlation between artemisinin content and trichome density was observed that could be useful for indirect selection of artemisinin yield in different accessions of A. annua. In addition, fifteen ISSR primers generated a total number of 222 amplified bands, consisting of 177 and 45 polymorphic and monomorphic loci across the 60 accessions, respectively. These results indicate that ISSR-PCR is a reliable tool for fingerprinting A. annua at the intra-population level. Our results altogether are valid contributions for gene bank management and Artemisia annua breeding programs.
