Showing 2 results for Gharbi
Volume 4, Issue 8 (6-2016)
Abstract
Oral literature is a part of the non-material culture. It is a rich kind of literature and includes a variety of legends, songs, proverbs, riddles, idioms and so on. Each of these types has rich dimensions for cultural analysing. "Ara" /ærɒ/ is a common expression or term in oral literature of Sheshtamad, Sabzevar region. It denotes to a series of processes and actions and activities that using native aesthetic elements, make a ritual and ceremonial aspects to objects and affairs. This article investigates the application of this local and popular idiomatic expresion for four ritual and ceremonial ceremonies like "Nakhl","Alam" , "Asbe Chobi" and the "Asbe Hizomi" . The research question is why does a particular action become a ritual and ceremonial act and the symbolic experesion of it become a ritual or ceremonial idiomatic experesion. The results indicates that each of these ceremonies show certain cultural and social meanings. "Ara" as an idiomatic expression is for highlighting the importance of the ritual and ceremonial meanings ,concepts and in general the importance of that social ceremony, art and aesthetic also is for showing this importance. This highlighting is with the transition from the realm of everyday life to social, ritual and symbolic life, so this idiomatic expression can be considered as a mixture of art, ritual and ceremonial concept. Moments of human life represents in social dimensions of the communal spirit of society. Due to the enormous significance of social reproduction and representation, the society benifies from main and the most important elements of itself ,that is art and aesthetic and ornamental elements to represent itself.
Sedigheh Sadat Mortazavi, Sedigheh Gharbi, Maryam Shahali,
Volume 12, Issue 1 (12-2020)
Abstract
ABSTRACT
Aims: Epithelial to mesenchymal transition (EMT) is an essential step in the developmental process, wound healing and cancer progression. In many cancers, EMT can increase aggressive properties including invasion, metastasis and Tumor resistance to apoptosis. Recently, miRNAs as a new class of non-coding RNAs that post-transcriptionally regulate gene expression have been demonstrated to have a crucial role in the regulation of EMT. However, the detailed mechanisms of miRNAs involvement in EMT in human cancer cells are still unclear. This study aimed to clarify this issue by using bioinformatics tools for predicting competent miRNAs target the main gens in EMT.
Materials and Methods: To ascertain an effective miRNA for the EMT, we assessed five genes from EMT/MET as key genes. Then, to predict the most suitable miRNA: target interactions, different online databases including DIANA, TargetScan, and miRSystem were applied.
Results: Possible targeting effects of different miRNAs on candidate genes were analyzed. Merging data from databases has shown that 11 miRNAs with strong possibility communally can be involved in EMT/MET.
Conclusion: To conclude, it can be predicted that according to high interaction scores of these elected miRNAs with candidate genes in the above-mentioned databases, these miRNAs probably can have critical roles in EMT/MET. Hence, these miRNAs can be introduced as appropriate candidates for future investigations.