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With the instrumentation of Mass Spectrometry (MS) and advances carried out in bioinformatic tools and databases, along with birth of nanotechnology in 1990s, biology experienced a dramatic revolution and new perspectives were found in molecular biology and medicine, agriculture, environmental sciences and pharmatiuticals. The most important one is systematic look at the entire organism and solving biological problems at the level of entire system viewed as an integrated and interacting network of genes, proteins and biochemical reactions (Systems Biology). In addition, :union: of biology and nanotechnology result in creation of nanobiotechnology. This paper provides an easy-to-read guide to the concepts of some of the major topics in today’s biology. Topics discussed here, include fundamentals of proteomics and systematic descriptions of the various types of studies in proteomics. After a brief review on the physical principles of nanotechnology, the application of one of its products, known as quantum dot in biology and particularly, proteomics studies, were discussed. This account covers the general principles and applications of new emerging fields in biology.

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Abstract: Level of the water table on reservoir is one of the parameters that effects on the seismic behavior of embankment dams. Water table in embankment dams changes every month of the year. Also changing of water table causes to the change of stress and strain in the body of dam. In this situation, earthquake can always happen. So to evaluate the effect of this parameter, Masjed Soleiman dam as a case study was selected. The Masjed Soleiman dam is a rock-fill type with clay core and a maximum height of 177m located on the Karoon River in the Southwest Iran. This embankment dam is located in Khuzestan province at the distance of 25.5 km to Masjed Soleiman town. Finite element model of Masjed Soleiman dam was constructed. The Mohr-coulomb elasticperfectly plastic constitutive model was taken into account to reflect the soil stress-strain relation. First, layer analysis was carried out considering 12 layers at the end of construction stage. Then, the analysis was continued considering the water table and weight of the dam reservoir in steady seepage condition. The 4 earthquake records in the far field condition were applied horizontally to the bedrock as the input for dynamic analysis. Then, by considering the result of dynamic analysis, changing of the maximum acceleration and maximum displacement in time domain was evaluated. In this study, to perform stability analysis and calculate the factor of safety, critical sliding surface on upstream and downstream, as reported by the consultant engineers, were considered. The semi- empirical Newmark method used for estimating permanent earthquake-related deformation of the slopes is based on the sliding block framework. This conceptual framework approximates the potential sliding mass as a rigid body resting on a rigid sloping base. Using the Newmark method, the equal dynamic factor of safety, minimum factor of safety and applied deformation were evaluated. For studying the water table effect on the behavior of embankment dams, 20 models were used with different water tables in the reservoir. In this study, dynamic analyses were done for 4 earthquake records and for 5 elevations of water table that were considered. Then the seismic response of embankment dam was investigated. The results showed that the level of the water table has low effect on occurred maximum acceleration and maximum displacement. Minimum factor of safety in the downstream critical slip surface was has increased when the water table elevation was increased. But this parameter in the upstream critical slip surface was decreased when the water table elevation was increased. Equal dynamic factor of safety in the downstream critical slip surface was increased when the water table elevation was increased. But the upstream critical slip surface was decreased when the water table elevation was increased to 0.6 height of the dam, and then the equal dynamic factor of safety was decreased. So water table elevation in the upstream wedge was in critical condition when the water table elevation was equal to 0.6 height of the dam. Permanent deformation occurred after the earthquake in the downstream critical slip surface was decreased when the water table elevation was increased but the permanent deformation occurred in the upstream wedge was increased when the water table elevation was increased.

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In order to ensure sustainable activities, companies independent upon working with defrent supplier's .In the manufacturing industries, raw material and assembly parts main comprise as much as 70 percent of production cost. For that, a purchasing department can play a vital role in reducing costs, and a purchasing manager's skill in performing his/her responsibility of choosing proper suppliers can greatly contribute to achieving that goal. This article focuses on the above-mentioned subject due to the importance of supplier choice for companies. Since the first times in history when the need for choosing proper suppliers was felt, many different methods and strategies have been utilized for such a task. Because of nature of that challenge, decision makers are faced with more than one criteria and high number of such criteria makes the challenge even more complex for them. Multi-criteria decision making has frequently been one of the approaches used by decision makers in the evaluation and selection of suppliers. In the research of this thesis a model of fuzzy multi-criteria and non-additive fuzzy integral has been presented for the supplier selection. The advantage of this model is that with the aid of Fuzzy Analytic Network Process the effects of the criteria on each other can be analyzed and with the fuzzy measure and fuzzy integral methods these interdependent relation between effects can be eliminated.

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Coffee Mix is one of the most popular instant drinks in the world, which is widely consumed. This product can cause nutritional problems due to the significant amount of sugar in the formulation. On the other hand, due to its beneficial properties, honey and ginger powder can be used in the instant coffee powder formula, to solve the anti-nutritional effects of sugar and to take advantage of the beneficial properties of ginger and honey powder. In this study, the effect of adding honey powder as a substitute for sugar in amounts of 0, 5, 10, 20, 30, and 35% of the consumed sugar and ginger powder in amounts of 0, 0.05, 0.1, 0.2, and 3 0.0 and 0.35% were added to the 3 in 1 instant coffee formulation and the physicochemical properties, phenolic compounds, antioxidant capacity and sensory properties and microbial properties of the coffee mixture were evaluated. The research results showed that adding honey and ginger powder to the instant coffee mixture improves its physicochemical properties and overall acceptability. Sensory tests conducted by the evaluators also determined that the treatment of 20% honey powder and 0.2% ginger and the treatment of 10% honey powder and 0.3% ginger were more favorable samples in terms of overall acceptability. The treatment of 30% honey powder and 0.3% ginger had the highest amount of phenolic compounds and antioxidant capacity. Therefore, the most appropriate treatment in terms of nutritional characteristics was the treatment of 30% honey powder and 0.3% ginger.