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Music is one of the effective factors in the global poem and literature. Particularly, if the poet’s work is composed based on the conscience truth and humanitarianism, and is far from any artificiality and artifice as well as is replete with various types of musical additives. Sadi Shirazi and Shamsuddin Kufi have made their odes more musical through selecting the two Tavil and Kamel meters (as the best models of expressing the man’s heartfelt feelings) and applying such various kinds of imagery as pun, symmetry, antithesis as well as appropriate words and the musical satire, in a accordance with the meaning and musical atmosphere of ode. The musical atmosphere of these two odes represents the increasing strangulation and the heavy atmosphere of Mugul attacks. In these two odes, the atmosphere is filled with anxiety, grief, internal blast, severity and violence, and one can observe these points in each rhythm of their ode letters. In addition to these advantages, Sheikh Shirazi’s being a non-Arab and the downfall governing the then Arab society following Mugul attack, have triggered some problems as the prosodic error of Esraf and Ejazeh in the music of these two worthwhile poets’ odes. An attempt has been made in this work to investigate the musical atmosphere of Sadi Shirazi and Shamsuddin Kufi’s odes through library research and by using structure analysis method.

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Nowadays, people with jobs such as judgment and attorney, which are mostly regarded as professions, spend great amounts of times with high efficiency. Continuous hard work in court and attorney workplaces is very strange. In this paper, we try to explain the strange captivation of judges and attorneys to work, under the term of workaholic behaviors. This research is a practical and uses descriptive-survey method. Also, in terms of relationship between the variables of the research, it is a correlative research and more specifically, based on Structural Equation Modeling. Research population includes judges and attorneys of Tehran who work in courts and law offices. The results of the research exhibit that there is a meaningful relationship between behavioral characteristics of judges and attorneys and their workaholics. Results also indicate that there is a significant and positive relationship between burn out and organizational commitment with workaholics.  

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Background: The importance of this research was to determine the prevalence of efflux pump genes among Acinetobacter baumannii isolates from hospitalized patients in Imam Reza hospital in Tabriz, Iran.
Materials and Methods: This descriptive study was conducted in the Imam Reza hospital, Tabriz, IR Iran during June 2013 to March 2014. Twenty-six strains were isolated from female patients (42.6%) and thirty-five from male patients (57.4%). Clinical specimens were cultured for isolation of the microbial agents of A. baumannii. The isolated bacteria were identified using biochemical tests. Disk diffusion susceptibility test was used to determine the antimicrobial susceptibility, and E-test methods were also used. The prevalence of efflux pump genes was detected by PCR and sequencing methods.
Results: The resistance of A. baumannii isolates against tested antibiotics was analyzed as follows: 51 (84%) to trimethoprim-sulfamethoxazole, 59 (98%) to ceftazidime, 60 (99%) to ciprofloxacin, 29 (48%) to amikacin, 46 (77%) to gentamicin, 30 (50%) to tobramicin, , 60 (99%) to imipenem,, 60 (99%) to meropenem,, 60 (99%) to ceftriaxon,, 60 (99%) to cefepime,, 60 (99%) to ofloxacin, 6 (11%) to colistin. By using E-test, 45 (73.3%) to imipenem, 57 (93.3%) to ciprofloxacin, 23 (38%) to amikacin were also analyzed. The prevalence of adeA, adeB, adeC, and abeMgenes was 54 (88.5%), 61 (100%), 57 (93.9%), and 60 (98.3%), respectively.
Conclusion: The result of this study showed high incidence of AdeABC efflux pump in MDR A. baumannii isolates and the growing number of nosocomial infections associated with XDR A. baumannii complex, leading to difficulties in antibiotic therapy.

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Variance of rainfed crops yield in different years is one of the main problems of world agriculture, specially in arid regions. There are two major groups of factors that might affect the development of agriculture.The First group are factors that are either constant in time or can be controlled with modifing methods and technologies. The second group are unsustainable factors related to microclimate of each region (such as the rate of rainfall, temperature, relative humidity, etc.) which we can not have any control on them; because climate modifing based on optimum need of any crop is possible only in Greenhouse conditions and in small scale, Therefore, recognizing the climatic parameters that influence crop yield is very important. By taking these factors into account, models can be prepared for forcasting the productivity and necessary plans can be made for providing the necessary crops in case of any shortage or saving them in stocks in case that there are more than enough. In this research, the effective climatic parameters in the productivity of rainfed wheat in west Azarbaijan province has been studied, and the relation of crop yield and climatic parameters has been investigated by making different multiple-regression models. Finally, some modells has been presented for forcasting the rainfed wheat productivity in west Azarbaijan province. Result of this study show annaully rainfall total and annaully frost days average parameters have the more important role in the produce of find model.

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One of the effective plant disease management strategies is based on the employment of resistance inducers. In the present study, to assay, the effects of Salicylic acid (chemical inducer) and Piriformospora indica (biological inducer) on wheat powdery mildew (Blumeria graminnis f. sp. tritici), the expression rate of Non-expresser of pathogenesis-related genes1 (NPR1) genewas evaluated using qPCR. For this purpose, Falat and Tajan cultivars were selected as susceptible and resistant genotypes to powdery mildew, respectively. To evaluate the rate of gene expression, the P. indica colonized Falat along with mock plants were inoculated with Powdery mildew. In another experiment, Falat treated with SA and control plants were inoculated with Powdery mildew 48 h after treatment with SA. Gene expression was assayed in Falat compared with resistant cv. Tajan. Sampling was carried out at 0, 6, 12, 24 and 48 hours after infection. Comparisons of gene expression patterns showed that after infection, the expression levels of NPR1 increased in induced and non-induced Falat and Tajan cultivars. The maximum gene expression levels were observed at 24 hours post infection. But the expression levels of the gene at this timewere much higher in induced treatments compared with control. The current study showed that NPR1 can be involved in resistance strategy. Thus, using NPR1 gene as a desired gene in genetic engineering for increasing the potential of plant resistance to pathogens can be considered. Moreover, the high response of NPR1 gene in induced plants indicated that both SA and P. indica play a critical role in inducing resistance.

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In Iranian mythology and since the beginning of creation war has been a current theme. Some Iranian gods, such as Bahrām, Mitrā, Bād, Hoom and Soroush, are fighting for peace, security and purity on behalf of Ahuramazdā against Angra Mainyu (Ahriman). Myths play an important role in the collective and subconscious memory. As such, they have a profound impact on religions, arts, literature and general culture of all times. Therefore, this article examines the gods of war in the legends of Chahārmahāl and Bakhtiāri, Lorestān and Kohgiluyeh and Boyerahmad province. The research context consists of legends written in Persian in Chaharmahāl and Bakhtiāri, Lorestān and Kohgiluyeh and Boyerahmad province. The purpose of this research is to explain and analyze the presence of mythological war gods in the legends of the above-mentioned provinces. Through a careful reading of this article, the reader will understand that the gods of war such as Bahrām, Soroush, Wind and Mehr are present in the legends of these provinces, sometimes superhuman and sometimes terrestrial with metamorphoses in their appearance and function.
 

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Abstract This comparative study examines the ar is one of the ly,rical works of the military that symbolically narrates the spiritual transformation of Bahram Gour, who housed seven martyrs from seven countries who were the symbol of their homeland's culture in seven palaces, and heard a story from them every night. The Shah overnight began on Saturday with the Princess of the Black Dome, and Adineh ended in the White Dome, which belonged to the "correctness" of the Iranian Princess. With a story centered on following Iranian culture and rationality, Dorsati transformed the Shah spiritually and brought him to immortality. While acquainting himself with Persian culture and literature, William Jones created the system of the Seven Springs based on the stories of the seven military figures. Aware of the influence of the number seven in various ethnic groups and its application in Eastern mythology, he set the foundation of the Haft Cheshmeh on the number seven, which corresponds to the seven figures in terms of morphology. , Examined the similarities and differences between the two systems and came to the conclusion that the young king of the Jones system finally evolved in dealing with a mythical maiden and reached immortality with the purification of body and soul. Haft Cheshmeh, in terms of structure and content, flows like streams from the areas of seven military palaces and calmly joins the ocean of Persian poetry and literature

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The Oriental culture, literature and myths have long been the focus of Orientalists and Western scholars. William Morris is a British poet who was interested in Persian poetry and literature. He was familiar with Persian culture and literature, and wrote “The Man Who Never Laughed Again” based on “The Black Dome” in Nizami Ganjavi’s Haft Peykar. He imitated the character, atmosphere of the story, the symbols, the colors, the costumes and other elements of the story from Haft Peykar. Haft Peykar or Haft Gonbad is one of Nizami’s lyrical poems that symbolically portrays the spiritual transformation of King Bahram of Iran. Bahram proposed to marry seven princesses from seven countries, and made them the first ladies of the seven palaces. He was the guest of one of them every night to spend time and rejoice when he heard stories. Finally, at the end of the week, when he was the guest of the Black Dome, Dorsati the Persian princess told a story about the Persian culture that influenced Bahram. This research, like other researches, has examined the impact of Nizami’s “The Black Dome” on William Morris’ work through the analysis of the content of the texts. It is based on library studies. In conclusion, this research is going to prove that William Morris’ work in terms of structure and content, like a refreshing seedling, is originated under the shade of the thick tree of Haft Peykar, then it has borne fruit in European literature.

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Objective: Verotoxin is a member of Shiga toxin family. This family contains AB protein toxins with an enzymatic (A) and a binding (B) compartment. Cells that have receptor (Gb3) are sensitive to cytotoxic effects of toxin. It has been shown that various tumor cells have Gb3 receptor and are selectively sensitive to apoptotic effect of verotoxin. Studies on tumor cell lines and laboratory animals have shown antineoplastic and antiangiogenesis effects of this toxin. The aim of this study was comparison of cytotoxic effect of verotoxin 1 on two cell lines: Vero (gold standard for evaluation of cytotoxic effect of Verotoxin) and Raji (a cell of a cultured line of lymphoblastoid cells derived from a Human Burkitt's lymphoma patients). Materials and Methods: The toxigenic strain was cultured and the production of toxin was evaluated by reverse passive latex agglutination test. Verotoxin 1 was purified by affinity chromatography. Vero and Raji cell were treated with serial dilutions of toxin, and viability was evaluated by MTT test. Results: Our result indicated that Verotoxin has cytotoxic effect on Raji cell lines. This effect is directly related to toxin concentration. Differences on cytotoxicity of toxin on Raji cells at 1:4-1:128 dilutions in relation to cytotoxicity of toxin on Vero cells at the same dilutions were considered statistically significant (P<0.05). But difference of cytotoxicity of toxin at higher dilutions was not significant. Conclusion: Our results revealed that Verotoxin has cytotoxicity on Vero and Raji cells, and this effect on Vero cells is more than Raji cells (P<0.05).

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The NCEP/NCAR monthly mean reanalysis data have been used to investigate the temporal and spatial variations of subtropical anticyclones over the Asia-Africa. The geopotential height and zonal and meridional wind components of 1000, 500, 200 and 100 hPa in a 30-year period (1971-2000) have been employed to determine the geographical characteristics, frequency and ridgeline of subtropical anticyclone in a domain of 60 -120 from April to October. The results revealed that there is an obvious difference about the location of subtropical anticyclones at lower, middle and upper levels. While Iranian anticyclone has been located in both middle and upper levels of troposphere, the Azores high, the Northwest African anticyclone, the Saudi Arabia anticyclone and the Tibetan anticyclone have just seen at lower, middle and upper levels of troposphere, respectively. The summertime geographical pattern of anticyclone center at 1000, 500, 200 and 100 hPa showed one mode (east of Atlantic Ocean), three mode (northwest Africa-Iran-Saudi Arabia), dispersed(from south china to west of Iran) and bimodal (Tibetan plateau-Iranian plateau) of distribution, respectively. In all levels, the maximum latitude of the ridgeline of subtropical anticyclone has related to august, which have been located over the northern flank of Tibetan plateau at 500 hPa, a wide region from the east to west of Asia at 200 hPa and Iran at 100 hPa. The most latitudinal jumping of ridgeline was from June to July, which has been reaching to 10 degrees along some longitudes.

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With the wide spread of electromagnetic waves in living environment, concerns about the harmful effects of these waves on human health have increased. However, many studies have been conducted on the biological effects of non-ionizing radiation, but there is no certainty about the effects of these radiation, especially on the nervous system. The achieved results from studies have many differences and even conflicting results have been reported. According to the previous studies, it is not yet concluded whether non-ionizing electromagnetic radiation damaging to the nervous system.  The purpose of this study is to analyze published articles about the effects of non-ionizing electromagnetic radiation on the nervous system in order to extract quantitative data on the effects of these waves. The purpose of this study is to analyze published articles about the effects of non-ionizing electromagnetic radiation on the nervous system in order to extract quantitative data on the effects of these waves. At first, the articles published in the ORSAA database were reviewed and divided into two categories: cellular and molecular parameters and neurological and cognitive parameters. The results obtained from the reviews and quantitative analyzes of the articles in the ORSAA database showed that in the category of cellular and molecular parameters, non-ionizing electromagnetic waves have the greatest effect on the change of enzyme activity and damage to proteins with 418 cases. Also, in the category of neurological and cognitive parameters, non-ionizing waves have the greatest effect on behavior and cognitive effects with 171 reported cases.
 

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The nose and nasal cavity and sinuses are a parts of the upper respiratory system and study the air passage into the upper component of human airway is important to improve or cure deficiency in human respiration cycle. The nose performs many important physiological functions, including heating, humidifying and filtering inspired air, as well as sampling air to smell. Previously, numerical modeling of turbulent flow in nasal cavity, sinus, pharynx and larynx has rarely been employed Since the 1990s, with the development of computed tomography technology and computational fluid dynamics, a number of numerical studies on gas and particle flows in realistic nasal cavities have been conducted and provided precise data for deeper insight of the nature of nasal airflows. Also, most of pioneering studies in this field have been developed to the investigation of only nasal cavity without sinuses especially maxillary sinus So, this research is tried to study details of turbulent airflow through all spaces in human head that air can flow through. For this purpose, study has based on computed tomography scans image of a 26-years old female head, neck and chest without problems in her respiratory system from Shahid Chamran hospital, Shiraz, Iran. It is found that, nasal resistance was contribute up to half of the total airway resistance within the first 2-3 cm of the airway and the majority of the flow in this region remained close to the septum wall and only a small proportion reached the olfactory region.

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Transportation Discrete Network Design Problem (TDNDP) is defined as the problem of selecting a subset of proposed projects (i.e. new highways) for construction, while holding the budget constraint, so as to minimize the total travel time of the network users. TDNDP has been often known as a problem with the bi-level programming formulation. At the upper level, this formulation allows for finding the optimal selection of the projects, while taking into account the route choice behavior of network users at its lower level. Such a formulation falls into the category of problems in the NP-Hard complexity class. These are resource-intensive problems which have not been exactly solved yet with any efficient algorithms. As a result, the main body of TDNDP related literature has ignored the exact solution of the problem and addressed TDNDP through heuristic and meta-heuristic approaches. These approaches contribute to find a rather high quality solution in a reasonable amount of time. Using heuristic and meta-heuristic algorithms is one way to overcome the complexity of NP-Hard problems like TDNDP. However, application of parallel computing still remains as another way to speed up the performance of such algorithms. Parallel computation aims at harnessing multiple computing resources, e.g. computer processors, to solve a certain problem. Different parallelization paradigms have been developed so far to parallelize solution algorithms. These paradigms generally address the two fundamental questions of how and when the required information should be exchanged among the processors. A master-slave (MS) parallelization paradigm is one of the basic paradigms in which one processor, namely the master, holds the main information of the problem. The master generates new jobs whenever needed, distributes them among other processors (i.e. slaves), and exploits them to work on the sent jobs. This paper is going to explore the application of parallel computation in a meta-heuristic algorithm in TDNDP. A parallel Ant Colony Algorithm (ACA), based on the study of Poorzahedy and Abulghasemi, is proposed with the MS parallelization paradigm. The Chicago Sketch transportation network is considered as a case study with 16 bi-directional proposed projects. The results are reported in three runs over a cluster of 8 processing cores for both single-core and parallel ACAs. According to the performances observed in this paper, parallel algorithms can achieve high quality solutions in 4000 seconds, while this happens for the single-core algorithms in 10000 seconds. The parallel ACA finds the exact solution of the problem in two instances out of three runs and in the other instance it converges to a solution with 0.07 percent error from the exact solution. The parallel performance of ACA is also reported along with that of the branch and bound algorithm. It is observed that the parallel branch and bound algorithm requires more than 32000 seconds running time to find the exact solution of the problem. More accurate comparisons, however, can only be achieved by running the single-core and parallel ACAs more than the three times used in this paper.

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Introduction: Amyloid beta (Aβ) is the major constituent of harmful plaques in the Alzheimer’s patients. Thus, study of Aβ and understanding its related molecular and cellular mechanisms is essential for diagnosis and therapeutic interventions. This study introduces a rapid, simple, and cost-effective technique for production and purification of this peptide, utilizing the expression of Aβ gene within bacterial system.
Materials and methods: Aβ gene was synthesized and transferred into the expression vector pET26b. After induction by Lactose and  24 hours of incubation for Aβ expression the cell sediment was analyzed for presence of recombinant peptide using SDS-PAGE and Western blot.  Then the purification of recombinant peptide was carried using nickel chloride affinity chromatography. Characterization of purified Aβ was performed by evaluating cell cytotoxicity in 25 µM and 50 µM concentrations using MTT assay on Alzheimer cell line model SH-SY5Y.
Results: Colony PCR and sequencing results showed the correct insertion of Aβ coding fragment into the expression vector. Presence of bands with the expected size in the results of SDS PAGE and western blot had confirmed successful expression of his-tagged recombinant peptide. MTT assay results showed the purified peptide has respectively 30 and 50% cytotoxicity for 25 µM and 50 µM concentrations.
Discussion: Production of amyloid beta peptide in bacterial hosts seems to be favorable. Obtaining Aβ peptide in soluble phase is an important advantage of this study. Hence according to toxicity of the purified peptide, it can be utilized for cell line treatments and further researches on Alzheimer disease.
 

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In this study a numerical model based on the finite element method is used to simulate the behavior of human lumber spine. Due to lack of realistic models, in the present work a lumber spine model is generated from Computational tomography (CT-Scan) images by Mimics 17 software. Also, according to the wide range of loading conditions, to achieve realistic results, optimized loads acquired from other researches are used. Human lumber spine model which is used in this study consists of five vertebrae, five discs, and all ligaments. Model is loaded under statically conditions and calculated with ANSYS-Abaqus 16 (Simulia Inc., Providence, USA) software. Obtained results are compared with other numerical simulation results and experimental measurements which are reported in other researches. Numerical modeling consists of six cases as follows: intervertebral rotation, interadiscal pressure and facet joint forces under the axial rotation and lateral bending with compressive follower force loadings. In all cases, intervertebral rotation, interadiscal pressure and facet joint forces are reported. Comparisons show that obtained results have a good agreement with experimental measurements. Therefore, results show that realistic model with optimized loadings predicted the behavior of lumber spine more accurate than other numerical models.

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Abstract
Free radicals cause many diseases in human. Antioxidants reduce the risk of cardiovascular disease and stroke by neutralizing free radicals and on the other hand, prevent progression of cancer. The natural antioxidant enhances antioxidant properties of plasma to prevent diseases such as heart disease, cancer, and stroke. Plants are a rich source of secondary compounds, which are the most important natural antioxidants.
In this study, Fumaria vaillanti aqueous, methanol and ethanol extracts were used to determine the anticancer effect of extracts on Breast Cancer Cells Lines BT-474, MDA-MB_231 after 24, 48 and 72h.
The highest percentage of cell death, according to the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) technique, has been reported in the aqueous extract on MDA-MB-231 cells after 72 hours at with IC₅₀ of 2 μg / ml.
The results of this study indicate that Fumaria vaillanti shows a significant antioxidant and cell toxicity effect and full potential of extracts can be realized by further studies on animal models and subsequent trials.
 

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Abstract
Ovarian cancer is one of the deadliest cancers in women causing abnormal cancerous cells that can spread and metastasize to other parts of the body. Secondary metabolites are highly variable in terms of structural and chemical properties and they are very important for plants survival. In this study, the extracts of two plants using three different solvents (water, ethanol 80% and methanol 80%) and water bath extraction method were obtained. phenolic compounds of extracts were determined by Folin Sioculto method. DPPH (2, 2-Diphenyl-1-picrylhydrazyl) and FRAP (Ferric reducing ability of plasma) methods were performed for determination of antioxidant properties. The amount of phenolic compounds in two plants was higher in 80% methanol solvent and the most antioxidant activities were observed in water solvent of extracts. Water solvent had the highest antioxidant activity and was selected to investigate the anti-cancer properties of extracts on ovarian cancer cells. Water extract of Ocimum basilicum within72 hours had the highest cytotoxic effect with an IC50 value of 1.105 ± 0.001 mg / ml. In study of antimicrobial activity by disc diffusion method, the highest antibacterial properties were only in ethanol extracts of two plants. In the measurement of MIC and MBC, ethanol and methanol extracts of Ocimum basilicum and water and ethanol extracts in Imatiens walleriana had the most inhibitory and bactericide effects.
 

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