Volume 11, Issue 4 (Winter 2007)
Abstract
A final and definite se... tence is valid only in the case of a finished event. The principle is that is should be real. However sentences are sometimes issued wrongly which is not in the interest of justice. This is why revision has been considered in legal procedures as a complementary means for the elimination of mistake. This article aims to clarify the principles of revision and to jurtappose them with other external regulations and rules. The purpose best practices based on practical and scientific applications of revision principles there are only five articles on legal revision leaving many regulations untouched which the present article will try to unfold.
Vahid zeraati, Parviz Abdolmaleki, Reza Hassan Sajedi, Abdolkarim Moazeni-Roodi,
Volume 13, Issue 1 (3-2022)
Abstract
Investigation of factors affecting endothelial cell proliferation is an essential part of angiogenesis studies. Given the importance of inhibiting angiogenesis in the treatment of cancers, and due to the side effects and high cost of anti-angiogenic drugs such as Avastin, the use of physical agents to aid in treatment and reduce the need for high doses of the drug is noteworthy. Magnetic fields are of interest due to their long-distance and non-invasive effects, and many studies have been conducted on their effects on biological phenomena, including angiogenesis, with inconsistent results. In the present study, the effect of a 2 mT alternating magnetic field with a frequency of 200 Hz and Austin on the proliferation of human umbilical vein endothelial cells (HUVEC) was investigated. Cells were treated for 48 hours under a mixture of 50 μg/ml solution of vascular endothelial growth factor (VEGEF) and Avastin at concentrations (zero (drug control), 50, 100, 200 and 400 μg/ml) as well as field treatment groups for They were exposed to magnetic fields for 3, 6, 12, 24 and 48 hours. Then, cell proliferation was assessed using Alamar Blue colorimetric test. Data were analyzed by three-way analysis of variance. According to the findings, the exposure times of 12, 24 and 48 hours showed a significant reduction in cell proliferation compared to the control group, but this difference was not significant in the 3 and 6 hour treatments. Also, the degree of interaction of these factors with each other on HUVEC proliferation was investigated.
