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Aims: A new generation of building materials is produced using computing and digital methods. Recombinant building materials have created new perspectives. The main purpose of research is to study, analyze and prioritize the computing of new materials in accordance with environment. The practical purpose of the research is to explain the concept and present strategies based on the use of appropriate materials to achieve the model of "healthy city".
Methods: It is qualitative-quantitative research in terms of methodology. Qualitative steps lead to the explanation of the conceptual framework of the research, and quantitative steps lead to prioritization of the strategies base on online questionnaire. Kappa coefficient has been used to confirm the reliability. A total of 386 questionnaires were collected and the results were analyzed using Spearman correlation.
Findings: Among the ten items extracted about the new materials used, four items with a high degree of significance were obtained: 1- Exposure to direct sunlight, 2- Material health (MSDS), 3- Ease of replacement and replacement, and 4- Degree of moisture absorption, respectively. 
Conclusion: The increasing risk of pandemics shows that the concept of the healthy city is not possible without the computing of new materials; an interdisciplinary field that requires a combined approach of green chemistry, biocomputing and materials-based computing. Computing new materials is an effective way to achieve the healthy city which is in need of "environmental education" and the "healthy city management" skill development.

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Aims: In the indoor space, the temperature and relative humidity are often controlled and even without the use of heating and cooling systems, the temperature and relative humidity changes in the indoor space are less than the outdoor space. Buildings are relatively protected against pollutants of external origin. The main problem of the research is to analyze and investigate the environmental effects of exposure to particles and gases that are released or produced inside the house; And especially the effect of these pollutants on the health of residents.

Methods: The research method of this study is based on logical reasoning. The scientific foundations of the subject are analyzed with a quasi-experimental approach, and the results are presented with the combined modeling method. In terms of methodology, in this research, chemical reactions carried out in indoor spaces are investigated. In this direction, the mechanisms and kinetics of reactions, the characteristics of different surfaces and the effect of factors such as light and temperature
will be investigated.

Findings: A healthy environment is a prerequisite for a healthy life for residents; This is as important in closed spaces as in open and semi-open spaces. Research
findings emphasize the special importance of micropollutants and their impact on residents' health.

Conclusion: Clarifying the importance and role of building materials in indoor air health is one of the most important achievements of this research. An achievement that above all emphasizes the importance of environmental education in promoting healthy buildings, bio-computing and the use of environmentally friendly materials.

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In the last month of 2019, an unknown virus appeared in Wuhan, China. Sequencing studies have shown that the virus is a new member of the coronavirus family, which mostly causes a respiratory disease with pneumonia-like symptoms. The new coronavirus consists of 25 proteins, including 4 important structural proteins and 15 non-structural proteins. Spike protein is one of the most important structural proteins on the surface of the virus; It is highly glycosylated and plays a key role in the virus binding to the host cells. The binding of glycans to proteins affects their structure and function in two ways; They lead to proper protein folding, and can play an important role in protein interactions, and also, by covering the surface of the protein, it causes the virus to escape from the immune system. So it is obvious that the study of glycan structures becomes more important when either a vaccine is going to be designed or glycan structures have important roles in the folding, activity, and interaction of a protein. Therefore, since the spike protein is a non-functional structural protein, the study of glycan structures is important for two goals of vaccine design and investigating the role of glycans in protein interactions. In this article, we are going to review the most important findings on spike protein glycosylation and compare the amount of glycosylation in different viruses, indicating the importance of glycan structures in designing an effective vaccine.

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Coronavirus disease 2019 (COVID-19) is a virally-induced pneumonia caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). This is the third disease-causing coronavirus after severe acute respiratory syndrome coronavirus (SARS-CoV) and the middle east respiratory syndrome coronavirus (MERS-CoV) which has been known in the human population in the 21^st century. To this date (20^th of Mehr, 1399), more than thirty-four million people have been infected by this virus and more than a million have lost their lives because of it which further signifies the importance of COVID-19 prevention and treatment. In this review article, we first take a look at the history of the famous coronaviruses and then introduce the genetic and pathophysiology of SARS-CoV-2 in a detailed manner. After discussing the related clinical manifestations, we shed a light on the treatments that have been assessed to this date. In the end, we will briefly discuss the vaccines that are currency being developed and highlight their success rate, so far. It is delightful to assert that out own research team is currently developing an oral and/or respiratory vaccine against SARS-CoV-2 which is composed of spike-surface decorated chitosan nanoparticles.