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Aims: The aim of this study was to extract, isolate, purify, identify and determine the percentage of two natural combinations of protocatechoic acid and gallic acid from Sumac with high efficiency. These compounds exhibit good antimicrobial, antiviral, antifungal, anti-diabetic, anti-insect and parasitic and antioxidant properties. Subsequently, to enhance the drug efficacy of these compounds, their silyl derivatives were prepared.
Materials & Methods: The Rhus coriria plant from the trees of the Naghadeh, from the trees of the Aras Baran and from the trees of the Shitaneh village was collected. They were dried in the shadow and grinding. After extraction, to identify two important compounds and their silyl derivatives, we use FT-IR, ¹H-NMR, ¹³C-NMR, GC-Mass, DSC, XRD and HPLC methods.
Findings: According to experiments, it can be concluded that the sample of Iranian Sumac fruits in Arasbaran region has the highest amounts of gallic acid (2.99%) and protocatechoic acid (2.902%). We also conclude that the type of soil and the location of growth of a genus are quite influential in its active ingredients, taste, and color. By silylation of these compounds, the lipophilic properties increase sharply, that is, they pass easily through the cell membrane and increase their judgment effect.
Conclusion: In this research work, two high-efficiency natural compounds were extracted from the samples of Sumac. Subsequently, due to their medicinal properties, silyl derivatives were prepared and their structure identified by spectroscopic methods. In this way, the permeability of the cell membrane easily done and the pharmacological effect of greatly increased.
 

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Background and Aim:
Oxidative stress factors are known to causes some metabolic disorders diseases. Therefore, preventing, or at least decreasing the amount of these factors may have a positive impact on prevention or improvement of the metabolic diseases. Recently, the herbal medicines are more considered due to more effectiveness. The present study was designed to evaluate anti-oxidant effect of sumac powder (Rhus coriaria L.).
Materials and Methods:
 In the present study, special parts of the sumac plant, dried at room temperature and powdered using laboratory mill. All samples were solubilized in methanol, and four concentrations (12.5, 25, 40 ،50 µ/ml) were prepared and the antioxidant activity of sumac powder measured by DPPH at a wavelength of 517 nm. Finally, the IC50 of all samples and the standard were calculated and compared with standard.
Results:
The methanol extracts of all sumac doses showed dose-dependent potent antioxidant activity. The results indicated that brown sumac powder (IC50 = 14/912) has the higher antioxidant activity compared to red sumac powder (IC50 = 27/385), which was lower than vitamin C (IC50 = 6/708).
Conclusion:
Brown sumac powder has a stronger antioxidant effect than red sumac powder, which can be effective in improving the antioxidant defense of the body, so we advise to consume brown sumac.