Volume 12, Issue 1 (2020)                   JMBS 2020, 12(1): 41-51 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Farzin H, Mohadese A, Kadoughani Sani S, Jamshidian Mojaver M. Effect of silver nanoparticles on Escherichia coli isolates from urinary tract infections resistant to several antibiotics. JMBS 2020; 12 (1) :41-51
URL: http://biot.modares.ac.ir/article-22-41896-en.html
1- Mashhad Branch, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Mashhad, Iran.
2- Master of Bacteriology, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran.
3- Master of Microbiology, Sabzevar Branch, Islamic Azad University, Sabzevar, Iran.
4- Mashhad Branch, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Mashhad, Iran. , m.jamshidian@rvsri.ac.ir
Abstract:   (1134 Views)
Abstract
Urinary tract infection is one of the most common and common bacterial infections, accounting for a significant proportion of hospital admissions (about 30-40%). Silver nanoparticles work by releasing silver ions against various bacteria. The fact that bacteria are not resistant to nanoparticles is very important and therefore will affect a wide range of bacteria.
Materials and Methods
In this study, 50 specimens of positive cultures with urinary tract infection referred to Imam Reza Hospital Laboratory in Bojnourd were studied. Resistance and susceptibility of the isolates were determined by disk diffusion method. In this study, antibacterial effects of silver nanoparticles were investigated by microdilution method using aqueous extract of Ganoderma leucidum. Vegetative electron microscopy was used to measure the size and shape of silver nanoparticles. In addition, infrared spectroscopy analysis was performed to investigate possible organic compounds involved in the synthesis of nanoparticles.
Results: The highest antibiotic resistance was related to ampicillin (84%). The resulting nanoparticles were 20 to 45 nm in size.
Conclusion:
The produced nanoparticles have antimicrobial activity and can be a good alternative in the treatment of antibiotic resistant infectious diseases.
 
Full-Text [PDF 247 kb]   (518 Downloads)    
Article Type: Original Research | Subject: Nanotechnology
Received: 2020/04/7 | Accepted: 2020/12/30 | Published: 2020/12/30

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.